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"Journey of a Therapeutic Antibody: From Preclinical to Clinical Proof of Concept Development"

Precision medicine is advancing rapidly, with therapeutic antibodies playing a crucial role in treating various diseases.

This eBook outlines the journey from discovery to clinical proof of concept, offering valuable guidance to help achieve clinical proof of concept and bring innovative treatments to patients.

Topics covered

• The evolution and significance of therapeutic antibodies, including monoclonal antibodies and ADCs
• Techniques for target expression, novel therapeutic characterization, and safety assessment
• Core clinical assessments, exploratory biomarkers, and dosing decisions
• Assays including tissue cross-reactivity, receptor occupancy, PK, immunogenicity, cytokine analysis, IHC, and multiplex IF, along with several case studies
• Considerations in partnering with preclinical and clinical testing providers

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Offered Free by: Precision for Medicine
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