Request Your Free Case Study Now:

"Enhancing Prodrug Solubility"

Download the Case Study to learn more.

Prodrugs are designed to address challenges related to the physicochemical properties of drugs, such as solubility, absorption and stability. ​ This case study highlights the successful development of a prodrug for a parent compound in Phase 3 clinical development for epilepsy. By integrating medicinal chemistry and ADME expertise, they achieved a remarkable 2,500-fold improvement in solubility using innovative phosphate-based prodrugs. ​ With rapid in vivo conversion and exceptional stability, this breakthrough offers a game-changing solution for treating epilepsy and other diseases, ensuring efficient drug delivery and enhanced patient outcomes.

Offered Free by: Syngene
See All Resources from: Syngene