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"Fiber-seq: Where Multiomic Chromatin Profiling Meets Long-Read Sequencing"

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Long-read sequencing (LRS) has reshaped how scientists explore the human genome. But to truly understand gene regulation, researchers need more sophisticated insight. Fiber-seq, a groundbreaking assay that layers chromatin context onto LRS, reveals a detailed view of how DNA is organized, accessed and regulated at a single-molecule resolution.

This whitepaper traces the rise of Fiber-seq, from its 2020 debut in Science to recent applications that are laying the groundwork for new discoveries in rare disease, neurobiology, and drug development. Learn how Fiber-seq overcomes the blind spots of short-read sequencing, replaces multiple parallel assays with a single experiment, and empowers multiomic insights into structurally complex regions of the genome.

Fiber-seq is now commercially available through EpiCypher, making this once-niche method ready for broader adoption. Download the whitepaper to learn how to elevate your genomics research by integrating Fiber-seq.

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