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"Powering Precision Oncology Research with the Clinical-Molecular Database"

Clinical-Molecular Database (CMDB) from Flatiron Health and Caris Life Sciences combines clinical data from Flatiron and molecular data from Caris. The CMDB powers research across life cycle phases with a special utility from discovery to clinical development.

The molecular breadth, clinical relevance, and scale of the CMDB unlock use cases that were not previously addressable with clinical trial datasets or other multi-omics sources. The combination of the deep, longitudinal clinical data from Flatiron with the extensive molecular testing data from Caris enables a comprehensive exploration of patient outcomes in the context of the broader real-world population.

This case study from Flatiron Health shows how the Clinical-Molecular Database can be used to identify genes and biological pathways associated with survival in cohorts treated with immunotherapies.

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