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"Comprehensive Characterization of mAb Charge Variants, PTMs, and CQAs Using A Microfluidic CE/MS System"

On Demand Webinar

Accurate characterization of charge variants and other critical quality attributes (CQAs) is essential for therapeutic mAb development and manufacturing. This webinar introduces the ZipChip microfluidic capillary electrophoresis system coupled with mass spectrometry (CE-MS), highlighting its ability to deliver rapid, MS-compatible separations with detailed structural insight.

Beyond charge variant analysis, we’ll explore applications in subunit analysis and peptide mapping, providing a comprehensive view of mAb heterogeneity. See how integrating microfluidic CE-MS can streamline workflows and deepen product understanding

What you will learn:

• How the ZipChip uses microfluidic capillary electrophoresis to seamlessly separate analytes based on their charge and deliver them directly into the mass spectrometer for rapid, detailed analysis
• How microfluidic CE-MS enables fast, high-resolution mAb CQA characterization and peak ID
• Discover the benefits that ZipChip has on characterization of mAbs, from intact protein analysis to peptide mapping, all within a single platform

Who should attend:

• Analytical Core Facilities within Biopharma
• Analytical Chemists
• Researchers/Scientist conducting Protein Characterization
• Managers/Directors in New Technology Implementation

Offered Free by: Repligen
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